ISWI remodelling of physiological chromatin fibres acetylated at Lysine 16 of Histone H4

• Main Authors: Klinker, Henrike, Mueller-Planitz, Felix, Nordenskiöld, Lars, Yang, Renliang, Forné, Ignasi, Liu, Chuan-Fa, Becker, Peter B.
• Other Authors: Dalal, Yamini
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/104784; http://hdl.handle.net/10220/20283
• Institution: Nanyang Technological University

ISWI is the catalytic subunit of several ATP-dependent chromatin remodelling factors that catalyse the sliding of nucleosomes along DNA and thereby endow chromatin with structural flexibility. Full activity of ISWI requires residues of a basic patch of amino acids in the N-terminal ‘tail’ of histone...