Glutathione activates type III secretion system through Vfr in Pseudomonas aeruginosa

• Main Authors: Zhang, Yani, Zhang, Chao, Du, Xiao, Zhou, Yun, Kong, Weina, Lau, Gee W., Chen, Gukui, Kohli, Gurjeet Singh, Yang, Liang, Wang, Tietao, Liang, Haihua
• Other Authors: Singapore Centre for Environmental Life Sciences and Engineering
• Format: Article
• Language: English
• Published: 2019
• Subjects: Glutathione; DRNTU::Science::Biological sciences; Type III Secretion System
• Online Access: https://hdl.handle.net/10356/104796; http://hdl.handle.net/10220/48631
• Institution: Nanyang Technological University

Glutathione (GSH) is the most abundant antioxidant in all living organisms. Previously, we have shown that a deletion mutant in the glutathione synthetase gene (ΔgshB) decreases the expression of type III secretion system (T3SS) genes of Pseudomonas aeruginosa. However, the mechanism remains elusive...