The effect of genotype and in utero environment on interindividual variation in neonate DNA methylomes

• Main Authors: Cheong, Clara Y., Holbrook, Joanna D., Barton, Sheila, Karnani, Neerja, Godfrey, Keith M., Teh, Ai Ling, MacIsaac, Julia L., Mah, Sarah M., Chong, Yap-Seng, Kwoh, Chee-Keong, Stünkel, Walter, Chen, Li, Kwek, Kenneth, Soh, Shu-E., Chong, Mary F. F., Meaney, Michael J., Ong, Mei-Lyn, Wong, Johnny, Buschdorf, Jan Paul, Kobor, Michael S., Pan, Hong, Dogra, Shaillay, McEwen, Lisa M., Saw, Seang-Mei, Gluckman, Peter D.
• Other Authors: School of Computer Engineering
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Biological sciences::Microbiology
• Online Access: https://hdl.handle.net/10356/104872; http://hdl.handle.net/10220/20310
• Institution: Nanyang Technological University

Integrating the genotype with epigenetic marks holds the promise of better understanding the biology that underlies the complex interactions of inherited and environmental components that define the developmental origins of a range of disorders. The quality of the in utero environment significantly...