TSpred : a web server for the rational design of temperature-sensitive mutants

• Main Authors: Tan, Kuan Pern, Khare, Shruti, Varadarajan, Raghavan, Madhusudhan, Mallur Srivatsan
• Other Authors: School of Computer Engineering
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Engineering::Computer science and engineering
• Online Access: https://hdl.handle.net/10356/104966; http://hdl.handle.net/10220/20390
• Institution: Nanyang Technological University

Temperature sensitive (Ts) mutants of proteins provide experimentalists with a powerful and reversible way of conditionally expressing genes. The technique has been widely used in determining the role of gene and gene products in several cellular processes. Traditionally, Ts mutants are generated by...