Characterisation of RIG-I-like receptor agonists for dengue virus therapy or vaccination

• Main Author: Ho, Victor Chin Yong
• Other Authors: Luo Dahai
• Format: Theses and Dissertations
• Language: English
• Published: 2019
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Immunology; DRNTU::Science::Biological sciences::Microbiology::Virology
• Online Access: https://hdl.handle.net/10356/105486; http://hdl.handle.net/10220/47846
• Institution: Nanyang Technological University

Dengue is a growing problem globally owing to failure in preventing the spread of the virus. Dengue virus (DENV) replication can be blocked through the activation of innate immune responses using RIG‐I‐like receptor agonists comprising naturally of double-stranded RNA containing a triphosphate group...