Chromatin laser imaging reveals abnormal nuclear changes for early cancer detection

• Main Authors: Chen, Yu-Cheng, Chen, Qiushu, Tan, Xiaotain, Chen, Grace, Bergin, Ingrid, Muhammad Nadeem Aslam, Fan, Xudong
• Other Authors: School of Electrical and Electronic Engineering
• Format: Article
• Language: English
• Published: 2019
• Subjects: DRNTU::Engineering::Electrical and electronic engineering; Laser-emission Microscopy; Colonoscopy
• Online Access: https://hdl.handle.net/10356/105495; http://hdl.handle.net/10220/47813; http://dx.doi.org/10.1364/BOE.10.000838
• Institution: Nanyang Technological University

We developed and applied rapid scanning laser-emission microscopy (LEM) to detect abnormal changes in cell nuclei for early diagnosis of cancer and cancer precursors. Regulation of chromatins is essential for genetic development and normal cell functions, while abnormal nuclear changes may lead to m...