Permeability and viscoelastic fracture of a model tumor under interstitial flow

• Main Authors: Tran, Quang D., Marcos, Gonzalez-Rodriguez, David
• Other Authors: School of Mechanical and Aerospace Engineering
• Format: Article
• Language: English
• Published: 2019
• Subjects: Engineering::Mechanical engineering; Permeability; Tumor
• Online Access: https://hdl.handle.net/10356/105581; http://hdl.handle.net/10220/50143
• Institution: Nanyang Technological University

Interstitial flow in tumors is a key mechanism leading to cancer metastasis. Tumor growth is accompanied by the development of a leaky vasculature, which increases intratumoral pressure and generates an outward interstitial flow. This flow promotes tumor cell migration away from the tumor. The natur...