Preparation and chiral separation of a novel immobilized cellulose-based chiral stationary phase in high-performance liquid chromatography

• Main Authors: Zhang, Zhen Bin, Peng, G. M., Wu, S. Q., Fang, Z. L., Wu, S. S., Ng, S. C., Zhang, Wei-Guang, Fan, Jun, Zheng, Sheng-Run
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Chemical engineering
• Online Access: https://hdl.handle.net/10356/105703; http://hdl.handle.net/10220/17956
• Institution: Nanyang Technological University

The chiral selector 6-azido-2, 3-di(p-chlorophenylcarbamoylated) cellulose was synthesized and further chemically immobilized onto 5-μm amino functionalized spherical porous silica gel. It was used as chiral stationary phase in high-performance liquid chromatography. Thirty racemates were successful...