“Smart” theranostic lanthanide nanoprobes with simultaneous up-conversion fluorescence and tunable T1–T2 magnetic resonance imaging contrast and near-infrared activated photodynamic therapy

• Main Authors: Zhang, Yan, Das, Gautom Kumar, Vijayaragavan, Vimalan, Xu, Qing Chi, Padmanabhan, Parasuraman, Bhakoo, Kishore K., Tamil Selvan, Subramanian, Tan, Timothy Thatt Yang
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Physics
• Online Access: https://hdl.handle.net/10356/105838; http://hdl.handle.net/10220/20951
• Institution: Nanyang Technological University

The current work reports a type of “smart” lanthanide-based theranostic nanoprobe, NaDyF4:Yb3+/NaGdF4:Yb3+,Er3+, which is able to circumvent the up-converting poisoning effect of Dy3+ ions to give efficient near infrared (980 nm) triggered up-conversion fluorescence, and offers not only excellent da...