Repurposing the anticancer drug cisplatin with the aim of developing novel Pseudomonas aeruginosa infection control agents

• Main Authors: Yuan, Mingjun, Chua, Song Lin, Liu, Yang, Drautz-Moses, Daniela Isabel, Yam, Joey Kuok Hoong, Aung, Thet Tun, Beuerman, Roger W., Salido, May Margarette Santillan, Schuster, Stephan Christoph, Tan, Choon-Hong, Givskov, Michael, Yang, Liang, Nielsen, Thomas Eiland
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2019
• Subjects: Cisplatin; DRNTU::Science::Biological sciences; Biofilm
• Online Access: https://hdl.handle.net/10356/105980; http://hdl.handle.net/10220/47416
• Institution: Nanyang Technological University

Antibiotic resistance threatens effective treatment of microbial infections globally. This situation has spurred the hunt for new antimicrobial compounds in both academia and the pharmaceutical industry. Here, we report how the widely used antitumor drug cisplatin may be repurposed as an effective a...