Enhancement of early cervical cancer diagnosis with epithelial layer analysis of fluorescence lifetime images

• Main Authors: Gu, Jun, Fu, Chit Yaw, Ng, Beng Koon, Liu, Lin Bo, Lim-Tan, Soo Kim, Lee, Caroline Guat Lay
• Other Authors: McLaughlin-Drubin, Margaret
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Engineering::Electrical and electronic engineering::Optics, optoelectronics, photonics
• Online Access: https://hdl.handle.net/10356/106050; http://hdl.handle.net/10220/26097
• Institution: Nanyang Technological University

This work reports the use of layer analysis to aid the fluorescence lifetime diagnosis of cervical intraepithelial neoplasia (CIN) from H&E stained cervical tissue sections. The mean and standard deviation of lifetimes in single region of interest (ROI) of cervical epithelium were previously sho...