Role of corin in trophoblast invasion and uterine spiral artery remodelling in pregnancy

• Main Authors: Cui, Yujie, Wang, Wei, Dong, Ningzheng, Lou, Jinglei, Srinivasan, Dinesh Kumar, Cheng, Weiwei, Huang, Xiaoyi, Liu, Meng, Fang, Chaodong, Peng, Jianhao, Chen, Shenghan, Wu, Shannon, Liu, Zhenzhen, Dong, Liang, Zhou, Yiqing, Wu, Qingyu
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Medicine
• Online Access: https://hdl.handle.net/10356/106141; http://hdl.handle.net/10220/23962
• Institution: Nanyang Technological University

In pregnancy, trophoblast invasion and uterine spiral artery remodelling are important for lowering maternal vascular resistance and increasing uteroplacental blood flow. Impaired spiral artery remodelling has been implicated in pre-eclampsia, a major complication of pregnancy, for a long time but t...