Identification of a new chemical class of antimalarials
The increasing spread of drug-resistant malaria strains underscores the need for new antimalarial agents with novel modes of action (MOAs). Here, we describe a compound representative of a new class of antimalarials. This molecule, ACT-213615, potently inhibits in vitro erythrocytic growth of all te...
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Main Authors: | Bozdech, Zbynek, Brunner, Ralf, Aissaoui, Hamed, Brun, Reto, Corminboeuf, Olivier, Delahaye, Stephane, Fischli, Christoph, Boss, Christoph, Heidmann, Bibia, Kaiser, Marcel, Kamber, Jolanda, Meyer, Solange, Papastogiannidis, Petros, Siegrist, Romain, Voss, Till, Welford, Richard, Wittlin, Sergio, Binkert, Christoph |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2013
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Online Access: | https://hdl.handle.net/10356/106461 http://hdl.handle.net/10220/12914 |
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Institution: | Nanyang Technological University |
Language: | English |
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