Nanoconfined β-sheets mechanically reinforce the supra-biomolecular network of robust squid sucker ring teeth
The predatory efficiency of squid and cuttlefish (superorder Decapodiformes) is enhanced by robust Sucker Ring Teeth (SRT) that perform grappling functions during prey capture. Here, we show that SRT are composed entirely of related structural “suckerin” proteins whose modular designs enable the for...
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sg-ntu-dr.10356-1066152021-01-10T11:51:34Z Nanoconfined β-sheets mechanically reinforce the supra-biomolecular network of robust squid sucker ring teeth Guerette, Paul A. Hoon, Shawn Ding, Dawei Amini, Shahrouz Masic, Admir Ravi, Vydianathan Venkatesh, Byrappa Weaver, James C. Miserez, Ali School of Materials Science & Engineering School of Biological Sciences Energy Research Institute @ NTU (ERI@N) DRNTU::Engineering::Materials::Biomaterials The predatory efficiency of squid and cuttlefish (superorder Decapodiformes) is enhanced by robust Sucker Ring Teeth (SRT) that perform grappling functions during prey capture. Here, we show that SRT are composed entirely of related structural “suckerin” proteins whose modular designs enable the formation of nanoconfined β-sheet-reinforced polymer networks. Thirty-seven previously undiscovered suckerins were identified from transcriptomes assembled from three distantly related decapodiform cephalopods. Similarity in modular sequence design and exon–intron architecture suggests that suckerins are encoded by a multigene family. Phylogenetic analysis supports this view, revealing that suckerin genes originated in a common ancestor ∼350 MYa and indicating that nanoconfined β-sheet reinforcement is an ancient strategy to create robust bulk biomaterials. X-ray diffraction, nanomechanical, and micro-Raman spectroscopy measurements confirm that the modular design of the suckerins facilitates the formation of β-sheets of precise nanoscale dimensions and enables their assembly into structurally robust supramolecular networks stabilized by cooperative hydrogen bonding. The suckerin gene family has likely played a key role in the evolutionary success of decapodiform cephalopods and provides a large molecular toolbox for biomimetic materials engineering. 2014-12-15T04:40:17Z 2019-12-06T22:14:57Z 2014-12-15T04:40:17Z 2019-12-06T22:14:57Z 2014 2014 Journal Article Guerette, P. A., Hoon, S., Ding, D., Amini, S., Masic, A., Ravi, V., et al. (2014). Nanoconfined β-sheets mechanically reinforce the supra-biomolecular network of robust squid sucker ring teeth. ACS Nano, 8(7), 7170-7179. 1936-0851 https://hdl.handle.net/10356/106615 http://hdl.handle.net/10220/24459 10.1021/nn502149u en ACS Nano © 2014 American Chemical Society. |
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DRNTU::Engineering::Materials::Biomaterials Guerette, Paul A. Hoon, Shawn Ding, Dawei Amini, Shahrouz Masic, Admir Ravi, Vydianathan Venkatesh, Byrappa Weaver, James C. Miserez, Ali Nanoconfined β-sheets mechanically reinforce the supra-biomolecular network of robust squid sucker ring teeth |
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The predatory efficiency of squid and cuttlefish (superorder Decapodiformes) is enhanced by robust Sucker Ring Teeth (SRT) that perform grappling functions during prey capture. Here, we show that SRT are composed entirely of related structural “suckerin” proteins whose modular designs enable the formation of nanoconfined β-sheet-reinforced polymer networks. Thirty-seven previously undiscovered suckerins were identified from transcriptomes assembled from three distantly related decapodiform cephalopods. Similarity in modular sequence design and exon–intron architecture suggests that suckerins are encoded by a multigene family. Phylogenetic analysis supports this view, revealing that suckerin genes originated in a common ancestor ∼350 MYa and indicating that nanoconfined β-sheet reinforcement is an ancient strategy to create robust bulk biomaterials. X-ray diffraction, nanomechanical, and micro-Raman spectroscopy measurements confirm that the modular design of the suckerins facilitates the formation of β-sheets of precise nanoscale dimensions and enables their assembly into structurally robust supramolecular networks stabilized by cooperative hydrogen bonding. The suckerin gene family has likely played a key role in the evolutionary success of decapodiform cephalopods and provides a large molecular toolbox for biomimetic materials engineering. |
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School of Materials Science & Engineering |
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School of Materials Science & Engineering Guerette, Paul A. Hoon, Shawn Ding, Dawei Amini, Shahrouz Masic, Admir Ravi, Vydianathan Venkatesh, Byrappa Weaver, James C. Miserez, Ali |
format |
Article |
author |
Guerette, Paul A. Hoon, Shawn Ding, Dawei Amini, Shahrouz Masic, Admir Ravi, Vydianathan Venkatesh, Byrappa Weaver, James C. Miserez, Ali |
author_sort |
Guerette, Paul A. |
title |
Nanoconfined β-sheets mechanically reinforce the supra-biomolecular network of robust squid sucker ring teeth |
title_short |
Nanoconfined β-sheets mechanically reinforce the supra-biomolecular network of robust squid sucker ring teeth |
title_full |
Nanoconfined β-sheets mechanically reinforce the supra-biomolecular network of robust squid sucker ring teeth |
title_fullStr |
Nanoconfined β-sheets mechanically reinforce the supra-biomolecular network of robust squid sucker ring teeth |
title_full_unstemmed |
Nanoconfined β-sheets mechanically reinforce the supra-biomolecular network of robust squid sucker ring teeth |
title_sort |
nanoconfined β-sheets mechanically reinforce the supra-biomolecular network of robust squid sucker ring teeth |
publishDate |
2014 |
url |
https://hdl.handle.net/10356/106615 http://hdl.handle.net/10220/24459 |
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1690658494553784320 |