The hollow fiber bioreactor as a stroma-supported, serum-free ex vivo expansion platform for human umbilical cord blood cells

• المؤلفون الرئيسيون: Xue, Cao, Kwek, Kenneth Y. C., Chan, Jerry Kok Yen, Chen, Qingfeng, Lim, Mayasari
• مؤلفون آخرون: School of Chemical and Biomedical Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2015
• الموضوعات: DRNTU::Science::Biological sciences::Human anatomy and physiology
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/106666; http://hdl.handle.net/10220/25034; http://dx.doi.org/10.1002/biot.201300320
• المؤسسة: Nanyang Technological University

The bone marrow microenvironment plays an integral role in the regulation of hematopoiesis. Residing stromal cells and the extracellular matrix in the bone marrow microenvironment provide biological signals that control hematopoietic stem cell (HSC) function. In this study, we developed a bio-mimeti...