Single input state polarization-sensitive optical coherence tomography with high resolution and polarization distortion correction

Abstract: In single input state polarization-sensitive optical coherence tomography (PS-OCT) with high resolution, the imperfections of quarter-wave plate (QWP) and the sensitivity roll-off mismatch between the two detection channels cause unpredictable polarization distortion. We present a correcti...

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Bibliographic Details
Main Authors: Xiong, Qiaozhou, Wang, Nanshuo, Liu, Xinyu, Chen, Si, Liang, Haitao, Chen, Shufen, Liu, Linbo
Other Authors: School of Chemical and Biomedical Engineering
Format: Article
Language:English
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/10356/106670
http://hdl.handle.net/10220/49648
http://dx.doi.org/10.1364/OE.27.006910
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Institution: Nanyang Technological University
Language: English
Description
Summary:Abstract: In single input state polarization-sensitive optical coherence tomography (PS-OCT) with high resolution, the imperfections of quarter-wave plate (QWP) and the sensitivity roll-off mismatch between the two detection channels cause unpredictable polarization distortion. We present a correction method based on the Jones matrix modeling of the system. In a single input PS-OCT system working at 840 nm with an axial resolution of ~2.3 μm, the method yielded better estimation of retardation and optic axis orientation with significantly reduced noise level, especially in weakly birefringent samples. Numerical simulations and quantitative imaging of a sample of known birefringence were performed to validate the performance. We further demonstrate the advantages of our approach with birefringence imaging of swine retina, rat aortic wall, and rat esophageal mucosa for potential clinical applications.