Revisiting De Novo drug design : receptor based pharmacophore screening

• المؤلفون الرئيسيون: Yoon, Ho Sup, Amaravadhi, Harikishore, Baek, Kwanghee
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2015
• الموضوعات: DRNTU::Science::Medicine
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/106721; http://hdl.handle.net/10220/25112
• المؤسسة: Nanyang Technological University

De novo drug design methods such as receptor or protein based pharmacophore modeling present a unique opportunity to generate novel ligands by employing the potential binding sites even when no explicit ligand information is known for a particular target. Recent developments in molecular modeling pr...