AppA : a web server for analysis, comparison, and visualization of contact residues and interfacial waters of antibody–antigen structures and models

• Main Authors: Nguyen, Minh N., Verma, Chandra Shekhar, Zhong, Pingyu
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2019
• Subjects: Contact Residues; Science::Biological sciences; Antibody–antigen
• Online Access: https://hdl.handle.net/10356/106852; http://hdl.handle.net/10220/49677
• Institution: Nanyang Technological University

The study of contact residues and interfacial waters of antibody–antigen (Ab-Ag) structures could help in understanding the principles of antibody–antigen interactions as well as provide guidance for designing antibodies with improved affinities. Given the rapid pace with which new antibody–antigen...