Redox-responsive mesoporous silica nanoparticles : a physiologically sensitive codelivery vehicle for siRNA and doxorubicin

• Main Authors: Ma, Xing, Teh, Cathleen, Zhang, Quan, Borah, Parijat, Choong, Cleo Swee Neo, Korzh, Vladimir, Zhao, Yanli
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Medicine
• Online Access: https://hdl.handle.net/10356/106859; http://hdl.handle.net/10220/25156
• Institution: Nanyang Technological University

Aims: Efficient siRNA/drug codelivery carriers can offer great promises to cancer treatment on account of synergistic effect provided from cancer-associated gene and anticancer drugs. In this work, a redox-responsive drug/siRNA codelivery vehicle based on mesoporous silica nanoparticles was fabricat...