Recent developments in vascular imaging techniques in tissue engineering and regenerative medicine

Adequate vascularisation is key in determining the clinical outcome of stem cells and engineered tissue in regenerative medicine. Numerous imaging modalities have been developed and used for the visualization of vascularisation in tissue engineering. In this review, we briefly discuss the very recen...

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Bibliographic Details
Main Authors: Upputuri, Paul Kumar, Sivasubramanian, Kathyayini, Chong, Mark Seow Khoon, Pramanik, Manojit
Other Authors: School of Chemical and Biomedical Engineering
Format: Article
Language:English
Published: 2015
Subjects:
Online Access:https://hdl.handle.net/10356/106902
http://hdl.handle.net/10220/25181
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Institution: Nanyang Technological University
Language: English
Description
Summary:Adequate vascularisation is key in determining the clinical outcome of stem cells and engineered tissue in regenerative medicine. Numerous imaging modalities have been developed and used for the visualization of vascularisation in tissue engineering. In this review, we briefly discuss the very recent advances aiming at high performance imaging of vasculature. We classify the vascular imaging modalities into three major groups: nonoptical methods (X-ray, magnetic resonance, ultrasound, and positron emission imaging), optical methods (optical coherence, fluorescence, multiphoton, and laser speckle imaging), and hybrid methods (photoacoustic imaging). We then summarize the strengths and challenges of these methods for preclinical and clinical applications.