“Turn-on” fluorescence probe integrated polymer nanoparticles for sensing biological thiol molecules

• Main Authors: Li, Menghuan, Li, Peizhou, Zhang, Quan, Selvan, Subramanian Tamil, Zhao, Yanli, Ang, Chung Yen, Tan, Si Yu, Lu, Yunpeng, Bai, Linyi
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Engineering::Nanotechnology
• Online Access: https://hdl.handle.net/10356/106905; http://hdl.handle.net/10220/25237
• Institution: Nanyang Technological University

A “turn-on” thiol-responsive fluorescence probe was synthesized and integrated into polymeric nanoparticles for sensing intracellular thiols. There is a photo-induced electron transfer process in the off state of the probe, and this process is terminated upon the reaction with thiol compounds. Confi...