Effects of polycaprolactone-based scaffolds on the blood-brain barrier and cerebral inflammation

• Main Authors: Choy, David Kim Seng, Nyein, Mya Aye, Lu, Jia, Nga, Vincent Diong Weng, Lim, Jing, Chou, Ning, Yeo, Tseng Tsai, Teoh, Swee-Hin
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Medicine::Tissue engineering
• Online Access: https://hdl.handle.net/10356/106998; http://hdl.handle.net/10220/25229
• Institution: Nanyang Technological University

Severe pathoanatomical and mechanical injuries compromise patient recovery and survival following penetrating brain injury (PBI). The realization that the blood–brain barrier (BBB) plays a major role in dictating post-PBI events has led to rising interests in possible therapeutic interventions throu...