NMR structures and localization of the potential fusion peptides and the pre-transmembrane region of SARS-CoV : implications in membrane fusion

• Main Authors: Mahajan, Mukesh, Bhattacharjya, Surajit
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/107413; http://hdl.handle.net/10220/25455
• Institution: Nanyang Technological University

Severe acute respiratory syndrome-associated coronavirus (SARS-CoV) poses a serious public health hazard. The S2 subunit of the S glycoprotein of SARS-CoV carries out fusion between the virus and the host cells. However, the exact mechanism of the cell fusion process is not well understood. Current...