Control of adipogenesis by the autocrine interplays between angiotensin 1–7/mas receptor and angiotensin II/AT1 receptor signaling pathways

• Main Authors: Than, Aung, Leow, Melvin Khee-Shing, Chen, Peng
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences::Biochemistry
• Online Access: https://hdl.handle.net/10356/107469; http://hdl.handle.net/10220/16679
• Institution: Nanyang Technological University

Angiotensin II (AngII), a peptide hormone released by adipocytes, can be catabolized by adipose angiotensin-converting enzyme 2 (ACE2) to form Ang(1-7). Co-expression of AngII receptors (AT1 and AT2) and Ang(1-7) receptors (Mas) in adipocytes implies the autocrine regulation of the local angiotensin...