Genetically determined height and coronary artery disease

• Main Authors: Kathiresan, Sekar, Kee, Frank, König, Inke R., Nelson, Christopher P., Hamby, Stephen E., Saleheen, Danish, Hopewell, Jenna C., Zeng, Lingyao, Assimes, Themistocles L., Kanoni, Stavroula, Willenborg, Christina, Burgess, Stephen, Amouyel, Phillipe, Anand, Sonia, Blankenberg, Stefan, Boehm, Bernhard Otto, Clarke, Robert J., Collins, Rory, Dedoussis, George, Farrall, Martin, Franks, Paul W., Groop, Leif, Hall, Alistair S., Hamsten, Anders, Hengstenberg, Christian, Kees Hovingh, G., Ingelsson, Erik, Kooner, Jaspal, Lehtimäki, Terho, März, Winifred, McPherson, Ruth, Wareham, Nicholas, Willer, Cristen J., Metspalu, Andres, Nieminen, Markku S., O'Donnell, Christopher J., Palmer, Colin N. A., Peters, Annette, Perola, Markus, Reilly, Muredach P., Ripatti, Samuli, Roberts, Robert, Salomaa, Veikko, Shah, Svati H., Schreiber, Stefan, Siegbahn, Agneta, Thorsteinsdottir, Unnur, Veronesi, Giovani, Zalloua, Pierre A., Erdmann, Jeanette, Deloukas, Panos, Watkins, Hugh, Schunkert, Heribert, Danesh, John, Thompson, John R., Samani, Nilesh J.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Medicine
• Online Access: https://hdl.handle.net/10356/107552; http://hdl.handle.net/10220/38521
• Institution: Nanyang Technological University

BACKGROUND: The nature and underlying mechanisms of an inverse association between adult height and the risk of coronary artery disease (CAD) are unclear. METHODS: We used a genetic approach to investigate the association between height and CAD, using 180 height-associated genetic variant...