A high-dimensional, stochastic model for twin-screw granulation – part 1: model description

• Main Authors: McGuire, Andrew D., Mosbach, Sebastian, Lee, Kok Foong, Reynolds, Gavin, Kraft, Markus
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2019
• Subjects: Granulation; Stochastic; Engineering::Chemical engineering
• Online Access: https://hdl.handle.net/10356/107589; http://hdl.handle.net/10220/50342
• Institution: Nanyang Technological University

In this work we present a novel four-dimensional, stochastic population balance model for twin-screw granulation. The model uses a compartmental framework to reflect changes in mechanistic rates between different screw element geometries. This allows us to capture the evolution of the material along...