Development of Barbier-Grignard-type alkylation reaction using unactivated alkyl halides in water.
The Barbier-Grignard-type alkylation reaction is one of the most important carbon-carbon bond formation reactions in organic synthesis. Classical methods developed for the Barbier-Grignard-type alkylation reaction are mainly limited to the use of moisture sensitive organometallic reagents such as Gr...
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Format: | Theses and Dissertations |
Language: | English |
Published: |
2008
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Online Access: | http://hdl.handle.net/10356/13623 |
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Institution: | Nanyang Technological University |
Language: | English |