Error studies for DNA data storage

Due to its large storage capacity and preservation ability, Deoxyribonucleic Acid (DNA) has become an attractive medium to store the increasing amount of information present today. Various research has been conducted to examine more ways to tap on the potential of DNA storage. However, due to the co...

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Main Author: Ng, Yi Mei
Other Authors: Erry Gunawan
Format: Final Year Project
Language:English
Published: Nanyang Technological University 2020
Subjects:
Online Access:https://hdl.handle.net/10356/136748
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1367482023-07-07T18:08:04Z Error studies for DNA data storage Ng, Yi Mei Erry Gunawan School of Electrical and Electronic Engineering EGUNAWAN@ntu.edu.sg Engineering::Electrical and electronic engineering Due to its large storage capacity and preservation ability, Deoxyribonucleic Acid (DNA) has become an attractive medium to store the increasing amount of information present today. Various research has been conducted to examine more ways to tap on the potential of DNA storage. However, due to the complex nature of DNA, errors such as deletions, insertions and substitutions can occur during the DNA synthesizing, sequencing or storage stage. Hence, data recovery becomes a challenge as the data directly retrieved from the medium would be altered due to the errors. Error studies of the DNA storage is crucial in understanding the error characteristics of the channel before deciding which error correcting codes to implement. In this final report, comprehensive error studies were conducted using various analysis methods. The error studies are based on the sequencing experimental results using Illumina Hi-Seq sequence technology. An experiment of 5000 oligos were simulated based on the results of error analyses, mainly taking substitution errors as consideration and using the substitution error probabilities. Subsequently, Reed-Solomon code was also implemented to correct the generated errors and the error performance after decoding was evaluated. Bachelor of Engineering (Electrical and Electronic Engineering) 2020-01-14T13:39:58Z 2020-01-14T13:39:58Z 2019 Final Year Project (FYP) https://hdl.handle.net/10356/136748 en A3299-182 application/pdf Nanyang Technological University
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Engineering::Electrical and electronic engineering
spellingShingle Engineering::Electrical and electronic engineering
Ng, Yi Mei
Error studies for DNA data storage
description Due to its large storage capacity and preservation ability, Deoxyribonucleic Acid (DNA) has become an attractive medium to store the increasing amount of information present today. Various research has been conducted to examine more ways to tap on the potential of DNA storage. However, due to the complex nature of DNA, errors such as deletions, insertions and substitutions can occur during the DNA synthesizing, sequencing or storage stage. Hence, data recovery becomes a challenge as the data directly retrieved from the medium would be altered due to the errors. Error studies of the DNA storage is crucial in understanding the error characteristics of the channel before deciding which error correcting codes to implement. In this final report, comprehensive error studies were conducted using various analysis methods. The error studies are based on the sequencing experimental results using Illumina Hi-Seq sequence technology. An experiment of 5000 oligos were simulated based on the results of error analyses, mainly taking substitution errors as consideration and using the substitution error probabilities. Subsequently, Reed-Solomon code was also implemented to correct the generated errors and the error performance after decoding was evaluated.
author2 Erry Gunawan
author_facet Erry Gunawan
Ng, Yi Mei
format Final Year Project
author Ng, Yi Mei
author_sort Ng, Yi Mei
title Error studies for DNA data storage
title_short Error studies for DNA data storage
title_full Error studies for DNA data storage
title_fullStr Error studies for DNA data storage
title_full_unstemmed Error studies for DNA data storage
title_sort error studies for dna data storage
publisher Nanyang Technological University
publishDate 2020
url https://hdl.handle.net/10356/136748
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