Mode of action study for a novel class of antimicrobial polymers against methicillin-resistant Staphylococcus aureus

• Main Author: Shi, Zhenyu
• Other Authors: Chan Bee Eng, Mary
• Format: Thesis-Master by Research
• Language: English
• Published: Nanyang Technological University 2020
• Subjects: Engineering::Bioengineering; Science::Biological sciences::Microbiology::Bacteria
• Online Access: https://hdl.handle.net/10356/136786
• Institution: Nanyang Technological University

The development of antibiotics has been hampered by the rapid evolution of antimicrobial resistance and lack of new mechanisms discovered. Membrane- polarizing cationic polymers have attracted attention due to their low propensity to induce resistance. A cationic polymer (labelled as PIM1) has been...