Formation and breakdown of death domain oligomers

Innate immune signaling involves formation of large signaling complexes through death domain homotypic interactions, allowing rapid signal amplification to facilitate inflammatory signaling. The formation and breakdown of these immune complexes allow modulation of innate immune responses. Elucidatin...

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Bibliographic Details
Main Author: Boo, Zhao Zhi
Other Authors: Wu Bin
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2020
Subjects:
Online Access:https://hdl.handle.net/10356/137519
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Institution: Nanyang Technological University
Language: English