Formation and breakdown of death domain oligomers
Innate immune signaling involves formation of large signaling complexes through death domain homotypic interactions, allowing rapid signal amplification to facilitate inflammatory signaling. The formation and breakdown of these immune complexes allow modulation of innate immune responses. Elucidatin...
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Format: | Thesis-Doctor of Philosophy |
Language: | English |
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Nanyang Technological University
2020
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Online Access: | https://hdl.handle.net/10356/137519 |
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Institution: | Nanyang Technological University |
Language: | English |