Turning straw into gold : building robustness into gene signature inference
Reproducible and generalizable gene signatures are essential for clinical deployment, but are hard to come by. The primary issue is insufficient mitigation of confounders: ensuring that hypotheses are appropriate, test statistics and null distributions are appropriate, and so on. To further improve...
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Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
2020
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Online Access: | https://hdl.handle.net/10356/137542 |
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Institution: | Nanyang Technological University |
Language: | English |