NIR-light-activated combination therapy with a precise ratio of photosensitizer and prodrug using a host-guest strategy

• Main Authors: Chen, Hongzhong, Zeng, Xiaowei, Tham, Phoebe Huijun, Phua, Fiona Soo Zeng, Cheng, Wei, Zeng, Wenfeng, Shi, Haoran, Mei, Lin, Zhao, Yanli
• 其他作者: School of Physical and Mathematical Sciences
• 格式: Article
• 語言: English
• 出版: 2020
• 主題: Science::Chemistry; Nanomedicine; Cancer Therapy
• 在線閱讀: https://hdl.handle.net/10356/137650
• 機構: Nanyang Technological University

The co-delivery of photosensitizers with prodrugs sensitive to reactive oxygen species (ROS) for light-triggered ROS generation and cascaded prodrug activation has drawn tremendous attention. However, the absence of a feasible method to deliver the two components at a precise ratio has impaired the...