Design and control of a piezo-driven flexure micromanipulator for the embryo biopsy

• Main Author: Zhang, Zezhong
• Other Authors: Ang Wei Tech
• Format: Thesis-Master by Research
• Language: English
• Published: Nanyang Technological University 2020
• Subjects: Engineering::Mechanical engineering; Engineering::Bioengineering
• Online Access: https://hdl.handle.net/10356/137807
• Institution: Nanyang Technological University

Trophectoderm (TE) biopsy is the most common method of embryo biopsy for Pre-implantation Genetic Testing (PGT). One of the critical problems in TE biopsy is how to dissect the zona pellucida (ZP) membrane of the embryo with minimal cell deformation, which requires high-precision micromanipulation....