WRINKLED1 transcription factor : how much do we know about its regulatory mechanism?

• Main Authors: Kong, Que, Ma, Wei
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Biological sciences; Arabidopsis; Transcription Factor
• Online Access: https://hdl.handle.net/10356/138303
• Institution: Nanyang Technological University

Many plant species produce and build up triacylglycerol (TAG) in their seeds as a main resource to provide carbon and energy during seedling development. Plant seed oils are important not only for human diets but also as renewable feedstock of industrial uses. WRINKLED1 (WRI1), an APETALA2 (AP2) transcription factor, plays an essential role in the transcriptional regulation of TAG biosynthesis as WRI1 regulates the expression of key genes in the glycolytic and fatty acid biosynthetic pathways. Recent work has identified intrinsic structural disorder in WRI1 that may affect the stability of the protein. Furthermore, WRI1 activity is modulated by post-translational modifications and interacting partners. These progresses shed light on regulatory functions of WRI1 at the molecular levels, paving new paths to the use of WRI1 for bioengineering of TAG in plants.