Single-cell analyses to decipher cell fate reprogramming

• Main Author: Xing, Qiaorui
• Other Authors: Koh Cheng Gee
• Format: Thesis-Doctor of Philosophy
• Language: English
• Published: Nanyang Technological University 2020
• Subjects: Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/138344
• Institution: Nanyang Technological University

Cellular reprogramming suffers from low efficiencies, resulting in heterogeneous populations. Therefore, ensemble measurements of the mixed population often mask the rare cells which are on the route to successful reprogramming. To de-convolute the heterogeneity, I have presented the single-cell roa...