Introduction : novel insights into TB research and drug discovery

Introduction : novel insights into TB research and drug discovery

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), kills more people than any other bacterium. TB control is threatened by the continued spread of drug resistance; multi-drug and extensively drug resistant Mtb require longer, more costly, treatment with multiple drugs causin...

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Main Author: Grüber, Gerhard
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2020
Subjects:
Science::Biological sciences::Biochemistry
Tuberculosis
Mycobacterium
Online Access:https://hdl.handle.net/10356/138549
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1385492023-02-28T16:57:52Z Introduction : novel insights into TB research and drug discovery Grüber, Gerhard School of Biological Sciences Science::Biological sciences::Biochemistry Tuberculosis Mycobacterium Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), kills more people than any other bacterium. TB control is threatened by the continued spread of drug resistance; multi-drug and extensively drug resistant Mtb require longer, more costly, treatment with multiple drugs causing worse side effects and have a lower likelihood of treatment success. The urgent need for better treatment options for drug resistant Mtb has led the World Health Organization to prioritize development of not only new individual antitubercular agents, but also new drug regimens. This introductory chapter of the special issue Novel insights into TB research and drug discovery within Progress in Biophysics and Molecular Biology, gives a short overview about the general problems of TB and the treatment of this disease today, and introduces the review topics within this issue. Accepted version 2020-05-08T02:31:46Z 2020-05-08T02:31:46Z 2020 Journal Article Grüber, G. (2020). Introduction : novel insights into TB research and drug discovery. Progress in Biophysics and Molecular Biology, 152, 2-5. doi:10.1016/j.pbiomolbio.2020.02.003 0079-6107 https://hdl.handle.net/10356/138549 10.1016/j.pbiomolbio.2020.02.003 32087187 2-s2.0-85080958151 152 2 5 en Progress in Biophysics and Molecular Biology © 2020 Elsevier Ltd. All rights reserved. This paper was published in Progress in Biophysics and Molecular Biology and is made available with permission of Elsevier Ltd. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Science::Biological sciences::Biochemistry
Tuberculosis
Mycobacterium
spellingShingle Science::Biological sciences::Biochemistry
Tuberculosis
Mycobacterium
Grüber, Gerhard
Introduction : novel insights into TB research and drug discovery
description Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), kills more people than any other bacterium. TB control is threatened by the continued spread of drug resistance; multi-drug and extensively drug resistant Mtb require longer, more costly, treatment with multiple drugs causing worse side effects and have a lower likelihood of treatment success. The urgent need for better treatment options for drug resistant Mtb has led the World Health Organization to prioritize development of not only new individual antitubercular agents, but also new drug regimens. This introductory chapter of the special issue Novel insights into TB research and drug discovery within Progress in Biophysics and Molecular Biology, gives a short overview about the general problems of TB and the treatment of this disease today, and introduces the review topics within this issue.
author2 School of Biological Sciences
author_facet School of Biological Sciences
Grüber, Gerhard
format Article
author Grüber, Gerhard
author_sort Grüber, Gerhard
title Introduction : novel insights into TB research and drug discovery
title_short Introduction : novel insights into TB research and drug discovery
title_full Introduction : novel insights into TB research and drug discovery
title_fullStr Introduction : novel insights into TB research and drug discovery
title_full_unstemmed Introduction : novel insights into TB research and drug discovery
title_sort introduction : novel insights into tb research and drug discovery
publishDate 2020
url https://hdl.handle.net/10356/138549
_version_ 1759856717530660864

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