Identifying genes in Parkinson’s disease : state of the art

• Main Authors: Chew, Elaine Guo Yan, Foo, Jia Nee, Tan, Eng-King
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Biological sciences::Genetics; Science::Biological sciences::Human anatomy and physiology::Neurobiology; Medical Genetics; Nervous System Diseases
• Online Access: https://hdl.handle.net/10356/138823
• Institution: Nanyang Technological University

Parkinson disease (PD) is a common neurodegenerative disorder which manifests as bradykinesia, movement rigidity and tremors in affected individuals. Our understanding of the genetic basis of PD has been steadily increasing since the initial report of a-synuclein mutations two decades ago. Mutations...