Real‐time imaging of dynamic cell reprogramming with nanosensors

• Main Authors: Wiraja, Christian, Yeo, David Chenloong, Tham, Khek-Chian, Chew, Sharon Wan Ting, Lim, Xinhong, Xu, Chenjie
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Chemical engineering; Cell Reprogramming; Molecular Beacons
• Online Access: https://hdl.handle.net/10356/139022
• Institution: Nanyang Technological University

Cellular reprogramming, the process by which somatic cells regain pluripotency, is relevant in many disease modeling, therapeutic, and drug discovery applications. Molecular evaluation of reprogramming (e.g., polymerase chain reaction, immunostaining) is typically disruptive, and only provides snaps...