Dynamics changes of CRISPR-Cas9 systems induced by high fidelity mutations

CRISPR-Cas9, a powerful genome editing tool, has widely been applied in biological fields. Since the discovery of CRISPR-Cas9 as an adaptive immune system, it has been gradually modified to perform precise genome editing in eukaryotic cells by creating double-strand breaks. Although it is robust and...

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Bibliographic Details
Main Authors: Zheng, Liangzhen, Shi, Jiahai, Mu, Yuguang
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2020
Subjects:
Online Access:https://hdl.handle.net/10356/139057
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Institution: Nanyang Technological University
Language: English