Soy-derived phytochemical genistein modifies chromatome topology to restrict cancer cell proliferation

• المؤلفون الرئيسيون: Dutta, Bamaprasad, Park, Jung Eun, Qing, Ivan Toh Yi, Kon, Oi Lian, Sze, Siu Kwan
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2020
• الموضوعات: Science::Biological sciences; Cell Proliferation; Chromatome
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/139282
• المؤسسة: Nanyang Technological University

Epidemiological data indicate that human cancer risk is significantly reduced by the consumption of soy-based foods containing the "phytoestrogen" genistein, which can signal via host cell estrogen receptors. While additional chemoprotective effects of genistein induced by epigenetic facto...