Catalytic asymmetric synthesis of Pt- and Pd-PCP pincer complexes bearing a para-N pyridinyl backbone

• Main Authors: Wong, Esther Hui Yen, Jia, Yu-Xiang, Li, Yongxin, Pullarkat, Sumod Appukuttan, Leung, Pak-Hing
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Chemistry; PCP Pincer Complexes; Para-N Pyridinyl Backbone
• Online Access: https://hdl.handle.net/10356/139574
• Institution: Nanyang Technological University

A diastereoselective catalytic asymmetric hydrophosphination reaction was performed using a palladacycle catalyst to produce chiral PCP phosphine ligand with high dr (95:5) and excellent enantioselectivity (>99% ee). Subsequent facile metalation of the chiral ligand with Pt and Pd metal salts yie...