Bioprinting of multimaterials with computer-aided design/computer-aided manufacturing

• Main Authors: Lee, Jia Min, Sing, Swee Leong, Yeong, Wai Yee
• Other Authors: School of Mechanical and Aerospace Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Mechanical engineering; Three-dimensional Bioprinting; Bioprinting
• Online Access: https://hdl.handle.net/10356/140114
• Institution: Nanyang Technological University

Multimaterials deposition, a distinct advantage in bioprinting, overcomes material's limitation in hydrogel-based bioprinting. Multimaterials are deposited in a build/support configuration to improve the structural integrity of three-dimensional bioprinted construct. A combination of rapid cross-linking hydrogel has been chosen for the build/support setup. The bioprinted construct was further chemically cross-linked to ensure a stable construct after print. This paper also proposes a file segmentation and preparation technique to be used in bioprinting for printing freeform structures.