Carbon-dot-mediated co-administration of chemotherapeutic agents for reversing cisplatin resistance in cancer therapy

• المؤلفون الرئيسيون: Feng, Tao, Chua, Huoy Jing, Zhao, Yanli
• مؤلفون آخرون: School of Materials Science & Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2020
• الموضوعات: Science::Chemistry; Cancer; Carbon Dots
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/140629
• المؤسسة: Nanyang Technological University

Chemotherapeutic DNA-modifying cisplatin and topoisomerase II (TOP2)-inhibiting doxorubicin (DOX) were co-administrated by full-color emissive carbon dots (CDs−Pt(IV)−DOX) through tumor intracellular environment responsive covalent bonds to successfully reverse the resistance of cisplatin in cancer...