Fabrication of poly (butadiene-block-ethylene oxide) based amphiphilic polymersomes : an approach for improved oral pharmacokinetics of Sorafenib

Fabrication of poly (butadiene-block-ethylene oxide) based amphiphilic polymersomes : an approach for improved oral pharmacokinetics of Sorafenib

Sorafenib (SFN), a hydrophobic anticancer drug, has several limitations predominantly poor aqueous solubility and hepatic first-pass effect, limiting its oral delivery that results into several other complications. Present study aims to develop Sorafenib loaded polymersomes using poly butadiene bloc...

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Bibliographic Details
Main Authors: Muhammad Adeeb Khan, Shaukat Ali, Venkatraman, Subbu S., Muhammad Farhan Sohail, Muhammad Ovais, Abida Raza
Other Authors: School of Materials Science and Engineering
Format: Article
Language:English
Published: 2020
Subjects:
Engineering::Materials
Sorafenib
Oral Delivery
Online Access:https://hdl.handle.net/10356/141202
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/141202

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