Lysosome-assisted mitochondrial targeting nanoprobe based on dye-modified upconversion nanophosphors for ratiometric imaging of mitochondrial hydrogen sulfide

• Main Authors: Li, Xiang, Zhao, Hui, Ji, Yu, Yin, Chao, Li, Jie, Yang, Zhen, Tang, Yufu, Zhang, Qichun, Fan, Quli, Huang, Wei
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Materials; Hydrogen Sulfide; Mitochondria
• Online Access: https://hdl.handle.net/10356/141345
• Institution: Nanyang Technological University

Hydrogen sulfide (H2S) is a versatile modulator in mitochondria and involved in numerous diseases caused by mitochondrial dysfunction. Therefore, many efforts have been made to develop fluorescent probes for mitochondrial H2S detection. However, these cationic small molecule probes are inapplicable...