Neutrophil‐mediated enhancement of angiogenesis and osteogenesis in a novel triple cell co‐culture model with endothelial cells and osteoblasts

• Main Authors: Herath, Thanuja D. K., Larbi, Anis, Teoh, Swee Hin, Kirkpatrick, C. James, Goh, Bee Tin
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Chemical engineering; Angiogenesis; Neutrophils
• Online Access: https://hdl.handle.net/10356/141510
• Institution: Nanyang Technological University

Repair and regeneration of critical‐sized bone defects remain a major challenge in orthopaedic and craniomaxillofacial surgery. Until now, attempts to bioengineer bone tissue have been hindered by the inability to establish proper angiogenesis and osteogenesis in the tissue construct. In the present...