Characterizing how acidic pH conditions affect the membrane-disruptive activities of lauric acid and glycerol monolaurate

• Main Authors: Valle-González, Elba Ruth, Jackman, Joshua Alexander, Yoon, Bo Kyeong, Park, Soohyun, Sut, Tun Naw, Cho, Nam-Joon
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Materials; Morphology; Vesicles
• Online Access: https://hdl.handle.net/10356/141544
• Institution: Nanyang Technological University

Fatty acids and monoglycerides are single-chain lipid amphiphiles that interact with phospholipid membranes as part of various biological activities. For example, they can exhibit membrane-disruptive behavior against microbial pathogens on the human skin surface. Supported lipid bilayers (SLBs) prov...