Regeneration of osteochondral defects in vivo by a cell‐free cylindrical poly(lactide‐co‐glycolide) scaffold with a radially oriented microstructure

• Main Authors: Dai, Yuankun, Shen, Tao, Ma, Lie, Wang, Dongan, Gao, Changyou
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Bioengineering; BMSCs; Controlled Directional Cooling
• Online Access: https://hdl.handle.net/10356/141582
• Institution: Nanyang Technological University

A scaffold with an oriented porous architecture to facilitate cell infiltration and bioactive interflow between neo‐host tissues is of great importance for in situ inductive osteochondral regeneration. In this study, a poly(lactide‐co‐glycolide) (PLGA) scaffold with oriented pores in its radial dire...