Establishment of an in vitro three‐dimensional model for cartilage damage in rheumatoid arthritis

• Main Authors: Peck, Yvonne, Leom, Li Ting, Low, Patricia Pei Fen, Wang, Dong-An
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Bioengineering; Cartilage; Tissue Engineering
• Online Access: https://hdl.handle.net/10356/141583
• Institution: Nanyang Technological University

Rheumatoid arthritis (RA) is a chronic inflammatory disease that leads to progressive joint destruction. To further understand the process of rheumatoid cartilage damage, an in vitro model consisting of an interactive tri‐culture of synovial fibroblasts (SFs), LPS‐stimulated macrophages and a primar...