Control of particle generation using ion concentration polarization (ICP) based microfluid platform

Microfluidics has been an important method for micro total analysis systems (TAS) making a major impact in many different fields. These devices have many unique advantages that allow us to have precision control on the flow process for in-situ observation. Ion exchange membranes (IEM) can be used to...

Full description

Saved in:
Bibliographic Details
Main Author: Toh, Kin Hun
Other Authors: Charles Yang Chun
Format: Final Year Project
Language:English
Published: Nanyang Technological University 2020
Subjects:
Online Access:https://hdl.handle.net/10356/141786
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English
id sg-ntu-dr.10356-141786
record_format dspace
spelling sg-ntu-dr.10356-1417862023-03-04T19:28:00Z Control of particle generation using ion concentration polarization (ICP) based microfluid platform Toh, Kin Hun Charles Yang Chun School of Mechanical and Aerospace Engineering MCYang@ntu.edu.sg Engineering::Mechanical engineering Engineering::Nanotechnology Microfluidics has been an important method for micro total analysis systems (TAS) making a major impact in many different fields. These devices have many unique advantages that allow us to have precision control on the flow process for in-situ observation. Ion exchange membranes (IEM) can be used to act as a filter allowing only specific ions to flow through creating an important particle transport phenomenon called Ion Concentration Polarization (ICP). This process occurs near the membrane and create an ion enrichment zone and an ion depletion zone. When high voltage is introduced to the microchannel, strong convective mixing was observed due to the formation of a vortex. In observation, results have shown that for a vortex to form, a low Reynolds number is required, and the effects are more prominent at lower ion concentration and higher voltage. In this experiment the phenomena of ICP was studied to see if it can be to control the size of particle generated. Controlling the size of the particle generated is an upcoming trend in nanotechnology and can also be applied in several fields. Tiny particles have a distinct benefit which allows its properties, both physical and chemical, to be different from the bulk material and they are based on the size of the particle. In this project, barium chloride and sodium sulfate are used as the two reactants to create the ICP phenomena with a pressure driven flow. The objective is to better understand how the active control of reaction rate and mixing in microfluidic devices, how reaction rate and mixing affects particle generation. Fabricating the device using polydimethylsiloxane (PDMS) and bonding the microchannel to a glass slide. The two reactants are injecting into the channel. Both reactants contain fluorescence to be able to observe the ICP phenomena and the output is collected to observe the particle size distribution. It was observed that ICP has a prominent effect in controlling the size of particle generation. The size of the particle reduced from 54mm at 0v to 35mm at 100v at the flow rate of 20 µl/hr. The experiment was conducted over 4 flow rates of 20,30,40 and 50 µl/hr. The results have shown that mixing effect has a significant effect on particle generation and the applied voltage plays a more pivotal role in the mixing performance as compared to the flow rate variation. Bachelor of Engineering (Mechanical Engineering) 2020-06-10T13:07:29Z 2020-06-10T13:07:29Z 2020 Final Year Project (FYP) https://hdl.handle.net/10356/141786 en A142 application/pdf Nanyang Technological University
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Engineering::Mechanical engineering
Engineering::Nanotechnology
spellingShingle Engineering::Mechanical engineering
Engineering::Nanotechnology
Toh, Kin Hun
Control of particle generation using ion concentration polarization (ICP) based microfluid platform
description Microfluidics has been an important method for micro total analysis systems (TAS) making a major impact in many different fields. These devices have many unique advantages that allow us to have precision control on the flow process for in-situ observation. Ion exchange membranes (IEM) can be used to act as a filter allowing only specific ions to flow through creating an important particle transport phenomenon called Ion Concentration Polarization (ICP). This process occurs near the membrane and create an ion enrichment zone and an ion depletion zone. When high voltage is introduced to the microchannel, strong convective mixing was observed due to the formation of a vortex. In observation, results have shown that for a vortex to form, a low Reynolds number is required, and the effects are more prominent at lower ion concentration and higher voltage. In this experiment the phenomena of ICP was studied to see if it can be to control the size of particle generated. Controlling the size of the particle generated is an upcoming trend in nanotechnology and can also be applied in several fields. Tiny particles have a distinct benefit which allows its properties, both physical and chemical, to be different from the bulk material and they are based on the size of the particle. In this project, barium chloride and sodium sulfate are used as the two reactants to create the ICP phenomena with a pressure driven flow. The objective is to better understand how the active control of reaction rate and mixing in microfluidic devices, how reaction rate and mixing affects particle generation. Fabricating the device using polydimethylsiloxane (PDMS) and bonding the microchannel to a glass slide. The two reactants are injecting into the channel. Both reactants contain fluorescence to be able to observe the ICP phenomena and the output is collected to observe the particle size distribution. It was observed that ICP has a prominent effect in controlling the size of particle generation. The size of the particle reduced from 54mm at 0v to 35mm at 100v at the flow rate of 20 µl/hr. The experiment was conducted over 4 flow rates of 20,30,40 and 50 µl/hr. The results have shown that mixing effect has a significant effect on particle generation and the applied voltage plays a more pivotal role in the mixing performance as compared to the flow rate variation.
author2 Charles Yang Chun
author_facet Charles Yang Chun
Toh, Kin Hun
format Final Year Project
author Toh, Kin Hun
author_sort Toh, Kin Hun
title Control of particle generation using ion concentration polarization (ICP) based microfluid platform
title_short Control of particle generation using ion concentration polarization (ICP) based microfluid platform
title_full Control of particle generation using ion concentration polarization (ICP) based microfluid platform
title_fullStr Control of particle generation using ion concentration polarization (ICP) based microfluid platform
title_full_unstemmed Control of particle generation using ion concentration polarization (ICP) based microfluid platform
title_sort control of particle generation using ion concentration polarization (icp) based microfluid platform
publisher Nanyang Technological University
publishDate 2020
url https://hdl.handle.net/10356/141786
_version_ 1759857427352649728